Here is the full list of all 46 System Shock achievements.
Collect all other Achievements
Destroy the Cyber Core in each Cyberspace level
Defeat SHODAN
Complete the game
Complete the game on the highest difficulties
Find all Audio Logs and Data Sticks on Citadel Station
Defeat all of the Cortex Reavers on Citadel Station
Use the Isolinear Chipset
Destroy all of SHODAN’s cameras and CPU Nodes
Find Skully, the Nightdive skull, on every level
Find and install every Weapon Modkit
Kill Edward Diego
Kill Edward Diego with the Laser Rapier
Kill an enemy with an Overhead Monitor
Kill two or more enemies with a single Railgun Projectile
Hack 20 enemies which have been acquired by the Target ID Hardware
Buy 10 Ammo Items from Ammo Depots
Kill two or more enemies with a single Plasma Core
Discover all firearms
Kill an enemy by bouncing a shot from the Ion Rifle
Kill 10 enemies while under the effects of the Berserk Combat Booster
Buy a Grenade from a Vending Machine
Use every type of Dermal Patch
Find the final version of all Hardware Attachments
Defeat Edward Diego while en route to the Life Pods
Start the Reactor Self-Destruct Countdown
Destroy the Antenna Relays on the Systems Engineering level
Jettison Beta Grove on the Executive level
Replace the Interface Demodulator and fix Subsystem Relay 428
Solve the Chess Puzzle in Delta Grove
Find the hidden Audio Log
Defeat Edward Diego
Recharge 20 times at a Power Station
Discover a Hidden Door
Solve 15 Circuit or Wire Panels without using a Logic Probe
Jump across the big ramp in the Storage level
Acquire a Laser Rapier
Destroy the Mining Laser
Disable the Safety Override for the Mining Laser
Deploy Isotope X-22 and enable the Radiation Shields
Consume 30 Food and Drink items
Destroy the Medical CPU Nodes
Salvage 100 Junk Items at Salvage Stations
Find the hidden Wrench. This looks familiar…
Kill three or more enemies with a single explosive weapon
Exit the Medical Healing Suites