Here is the full list of all 76 Cave Story+ achievements.
Normal Ending
Completed Easy Mode
Defeated the Undead Core!
Defeated the Muscle Doctor!
Defeated the Doctor!
Defeated Misery!
Defeated the Twin Dragons!
Found and collected all Missile upgrades
Obtained the Bubbline!
Defeated Ironhead!
Defeated the Core!
Obtained the Super Missile Launcher!
Defeated Balrog, yet again...
Defeated Monster X!
Defeated Puu Black!
Obtained the Arms Barrier!
Obtained the Turbocharge!
Obtained the Blade!
Defeated Toroko...
Obtained the Life Pot!
Accumulated XX,XXX of damage
Defeated Omega!
Obtained the Machine Gun!
Defeated Curly...
Defeated Balfrog!
Defeated Balrog!
Defeated Balrog, again...
Obtained the Fireball!
Obtained the Map System!
Defeated Igor!
Obtained the Missile Launcher!
Obtained the Polar Star!
For the rest of us!
Obtained the Snake!
Obtained the Spur!
Obtained the Nemesis!
Obtained Chako's Lip Stick!
Obtained the Tow Rope!
Obtained Curly's Panties!
Obtained the Whimsical Star!
Obtained the Alien Medal!
Obtained the 290 Counter!
Found Mister Little!
Obtained Ma Pignon!
Obtained the Iron Bond!
Defeated the Red Ogre!
Defeated G-Clone!
Defeated Heavy Press!
Defeated Ballos!
Bad Ending
Mask Mimiga Ending
No Life Capsules (Good Ending)
No Life Capsules (Best Ending)
Completed Hard Mode
Completed Blood Stained Sanctuary
Completed Blood Stained Sanctuary in Less Than 3:00
Completed Blood Stained Sanctuary in Less Than 4:00
Completed Blood Stained Sanctuary in Less Than 5:00
Completed Blood Stained Sanctuary in Less Than 6:00
Completed Boss Attack
Completed Boss Attack in Less Than 8:00
Completed Boss Attack in Less Than 10:00
Completed Boss Attack in Less Than 12:00
Completed Boss Attack in Less Than 15:00
Completed Wind Fortress in Less Than 4:00
Completed Wind Fortress in Less Than 5:00
Completed Wind Fortress in Less Than 6:00
Completed Wind Fortress in Less Than 7:00
Played Cave Story on April 29th!
Spared Eggfish
Beat Omega with Jenka's Puppy
Saved Curly Brace
Returned Mister Little back home
Found and collected all Life Capsules
Beat by Toroko