Here is the full list of all 43 Prototype 2 achievements. It takes around 20-25 hours to unlock all of the achievements on Windows.
Complete the game.
Complete the game on HARD difficulty.
Complete LABOR OF LOVE.
Destroy 5 vehicles using a Finisher.
Mount a helicopter using Whipfist.
Spend at least 25 consecutive seconds in the air (helicopters don't count).
Reach the highest point in the world.
Acquire 30 upgrades through Consumes.
Complete FALL FROM GRACE.
Acquire a Mutation in each of the 5 categories.
20 or more kills with a single Hammerfist dive attack.
Consume 10 //BLACKNET targets.
Acquire 10 upgrades through Consumes.
Stealth Consume 50 Blackwatch troopers.
Destroy a single Lair.
Acquire 5 Mutations.
Complete NATURAL SELECTION.
Counter enemy attacks 20 times using Shield.
Deflect 5 missiles at enemies using Shield Block.
10 or more kills with a single Black Hole attack.
Trigger 50 alerts.
Complete a //BLACKNET operation.
Dismember a Brawler.
Acquire a Prototype Power.
5 consumes in 10 seconds or less.
Meet Father Guerra.
Complete RESURRECTION.
Complete MEET YOUR MAKER.
Find all BlackBoxes.
Defeat all Field Ops teams.
Destroy a Strike Team in 15 seconds or less.
Simultaneously kill 2 Brawlers using a single Devastator.
Stealth hijack 5 tanks or APCs.
Destroy 10 Blackwatch tanks, APCs or helicopters using a single hijacked tank or APC.
Travel a half mile using only Wall Run, Glide, Jump and Air Dash.
10 or more kills using a single Bio-Bomb.
Destroy 5 helicopters using Pack Leader.
Weaponize 10 vehicles.
Karate kick a helicopter.
Acquire all 46 upgrades through Consumes.
Destroy all Lairs.
Complete all //BLACKNET dossiers.
Fully upgrade Heller.