Here is the full list of all 58 Lucius achievements. It takes around 40-50 hours to unlock all of the achievements on Windows.
Open safe without hints.
Kill 4 persons.
Kill 3 persons.
Talk to to people 10 times.
Read 20 journal entries.
Kill Gene.
Kill Mary.
Kill 5 persons.
Kill 6 persons.
Kill 7 persons.
Kill 8 persons.
Kill 9 persons.
Kill 10 persons.
Kill 11 persons.
Kill 12 persons.
Kill 13 persons.
Kill 14 persons.
Kill 15 persons.
Kill 16 persons.
Kill 17 persons.
Kill 18 persons.
Kill 19 persons.
Kill 20 persons.
Get fifth level for mindcontrol.
Get fifth level for telekenesis.
Get fifth level for memoryerase.
Get fifth level for combustion.
Use lesser combustion 5 times.
Use lesser combustion 10 times.
Use memory-erase 5 times.
Use memory-erase 10 times.
Use mindcontrol 5 times.
Use mindcontrol 10 times.
Assist on 3 suicides.
Find secret chamber before chapter seven.
Collect 20 items.
Shoot 5 persons.
Shoot someone.
Take 20 pictures.
Open 50 drawers.
Break 50 objects.
Break 30 objects.
Break 20 objects.
Break 10 objects.
Run 26 miles.
Cycle 10 miles.
Turn a cross five times.
Turn on the television 5 times.
Turn off lights 20 times.
Find two ways to listen music from the music box.
Get spotted 5 times.
Combine 6 items.
Let five people burn.
Play 20 hours.
Play 40 hours.
Escape from storage jail.
Complete all tutorial's.
Complete chores for all the presents.