Here is the full list of all 100 Spellbook Demonslayers achievements.
Reach level 125 with 77 Malice.
Reach level 125 with any Spellbook.
Level up Synthesis to level 4.
Obtain 20 buffs at once.
Level up Trailblazer to level 4.
Reach level 50 with Enigma.
Unlock Enigma
Level up Deathbound to level 4.
Survive 20 minutes with 22 or more Malice.
Survive 20 minutes with 33 or more Malice.
Survive 20 minutes with 44 or more Malice.
Survive 20 minutes with 55 or more Malice.
Survive 20 minutes with 66 or more Malice.
Survive 20 minutes with 77 Malice.
Level up Bloodletting to level 4.
Level up Fracture to level 4.
Survive 20 minutes with 13 or more Malice.
Level up Demon Feast to level 4.
Level up Cremation to level 4.
Survive 20 minutes with 7 or more Malice.
Level up Eyepopper to level 10.
Level up Meltdown to level 10.
Reach level 50 with Jeanne.
Level up this spell to level 10.
Level up Throne of Darkness to level 10.
Level up Dark Moon to level 4.
Reach level 50 with Sly.
Level up Flame Lance to level 10.
Level up Bloodspark to level 10.
Level up Acid Breath to level 10.
Reach level 50 with Berry.
Level up Cataclysm Sigil to level 10.
Level up Toxic Blizzard to level 10.
Level up Timmy & Tommy to level 10.
Level up Fire of Sinai to level 10.
Reach level 50 with Vella.
Level up Midnight Sigil to level 10.
Level up Agni's Sigil to level 10.
Successfully complete any stage with 4 copies of the same spell at level 10.
Level up Shotgun to level 4.
Gamble at Ibrahim's Emporium 4 times in a single run.
Reach level 50 with Tammy.
Level up Overload to level 10.
Level up Frost Shear to level 10.
Level up Blood Barrage to level 10.
Level up Winter Sigil to level 10.
Open 69 treasure chests.
Level up Star Scourge to level 10.
Reach level 50 with Eden.
Achieve a movement speed of 420% or higher.
Level up Shrinkage to level 10.
Level up Airavata's Arrival to level 10.
Level up Acrobatics to level 4.
Reach level 100 with any Spellbook.
Level up Skewer to level 4.
Obtain 10 buffs at once.
Level up Thunderswarm to level 10.
Level up Indra's Sigil to level 10.
Reach level 50 with Wolfe.
Level up Blitzkrieg to level 10.
Level up Deadly Aim to level 4.
Level up Lethality to level 4.
Level up Nightshade to level 4.
Play 3 runs.
Activate a Revive.
Level up Samsara to level 4.
Reach level 80 with any Spellbook.
Level up Shrine Maiden to level 4.
Level up Revengeance to level 4.
Level up Reverberation to level 4.
Level up Freezing Rain to level 10.
Level up Fortification to level 4.
Reach level 50 with Astrid.
Have 4 level 10 Spells at once.
Level up Inferno to level 10.
Achieve a Regeneration amount of 77 or higher.
Level up Juggernaut to level 4.
Reach level 60 with any Spellbook.
Level up Intensity to level 4.
Reach level 50 with Speare.
Level up Clairvoyance to level 4.
Reach level 40 with any Spellbook.
Level up Monsoon to level 10.
Level up Ardor to level 10.
Level up Slipstream to level 4.
Level up Spectre Shot to level 10.
Survive for 4 minutes.
Earn 13 or more Astral Flowers in a single run.
Level up Brutality to level 4.
Level up Thickening to level 4.
Obtain 5 buffs at once.
Survive for 13 minutes to begin the Slaughter.
Level up Mending to level 4.
Reach level 20 with any Spellbook.
Level up Brainpower to level 4.
Level up Madame Death to level 10.
Reach level 125 with 77 Malice with every spellbook.
Obtain 30 buffs at once.
Obtain 40 buffs at once.
Obtain 50 buffs at once.