Here is the full list of all 43 Prototype 2 achievements. It takes around 20-25 hours to unlock all of the achievements on Windows.
Fully upgrade Heller.
10 or more kills with a single Black Hole attack.
Acquire all 46 upgrades through Consumes.
Destroy 5 vehicles using a Finisher.
Destroy 5 helicopters using Pack Leader.
Counter enemy attacks 20 times using Shield.
20 or more kills with a single Hammerfist dive attack.
Complete the game.
Complete the game on HARD difficulty.
Complete LABOR OF LOVE.
Complete all //BLACKNET dossiers.
Destroy a Strike Team in 15 seconds or less.
Mount a helicopter using Whipfist.
Destroy 10 Blackwatch tanks, APCs or helicopters using a single hijacked tank or APC.
Stealth hijack 5 tanks or APCs.
Travel a half mile using only Wall Run, Glide, Jump and Air Dash.
Find all BlackBoxes.
Destroy all Lairs.
Defeat all Field Ops teams.
10 or more kills using a single Bio-Bomb.
Acquire 30 upgrades through Consumes.
Spend at least 25 consecutive seconds in the air (helicopters don't count).
Reach the highest point in the world.
Complete FALL FROM GRACE.
Weaponize 10 vehicles.
Deflect 5 missiles at enemies using Shield Block.
Consume 10 //BLACKNET targets.
Karate kick a helicopter.
Acquire a Mutation in each of the 5 categories.
Simultaneously kill 2 Brawlers using a single Devastator.
5 consumes in 10 seconds or less.
Acquire 10 upgrades through Consumes.
Complete NATURAL SELECTION.
Destroy a single Lair.
Stealth Consume 50 Blackwatch troopers.
Trigger 50 alerts.
Acquire 5 Mutations.
Complete a //BLACKNET operation.
Dismember a Brawler.
Acquire a Prototype Power.
Meet Father Guerra.
Complete RESURRECTION.
Complete MEET YOUR MAKER.