Here is the full list of all 43 Prototype 2 achievements. It takes around 20-25 hours to unlock all of the achievements on Windows.
Complete the game on HARD difficulty.
Destroy a Strike Team in 15 seconds or less.
Fully upgrade Heller.
Counter enemy attacks 20 times using Shield.
Destroy 5 helicopters using Pack Leader.
Simultaneously kill 2 Brawlers using a single Devastator.
Destroy 10 Blackwatch tanks, APCs or helicopters using a single hijacked tank or APC.
10 or more kills with a single Black Hole attack.
20 or more kills with a single Hammerfist dive attack.
10 or more kills using a single Bio-Bomb.
Mount a helicopter using Whipfist.
Spend at least 25 consecutive seconds in the air (helicopters don't count).
Complete the game.
Complete LABOR OF LOVE.
Defeat all Field Ops teams.
Destroy all Lairs.
Acquire all 46 upgrades through Consumes.
Find all BlackBoxes.
Complete all //BLACKNET dossiers.
Destroy 5 vehicles using a Finisher.
Acquire 30 upgrades through Consumes.
Travel a half mile using only Wall Run, Glide, Jump and Air Dash.
Reach the highest point in the world.
Complete FALL FROM GRACE.
Weaponize 10 vehicles.
Acquire a Mutation in each of the 5 categories.
Stealth Consume 50 Blackwatch troopers.
Destroy a single Lair.
Consume 10 //BLACKNET targets.
Acquire 5 Mutations.
Stealth hijack 5 tanks or APCs.
Acquire 10 upgrades through Consumes.
Karate kick a helicopter.
Complete NATURAL SELECTION.
Deflect 5 missiles at enemies using Shield Block.
Trigger 50 alerts.
5 consumes in 10 seconds or less.
Complete a //BLACKNET operation.
Dismember a Brawler.
Acquire a Prototype Power.
Meet Father Guerra.
Complete RESURRECTION.
Complete MEET YOUR MAKER.