Here is the full list of all 43 Prototype 2 achievements. It takes around 20-25 hours to unlock all of the achievements on Windows.
Complete the game on HARD difficulty.
Fully upgrade Heller.
Spend at least 25 consecutive seconds in the air (helicopters don't count).
Destroy 5 helicopters using Pack Leader.
Find all BlackBoxes.
Defeat all Field Ops teams.
Acquire all 46 upgrades through Consumes.
Destroy all Lairs.
Destroy a Strike Team in 15 seconds or less.
Stealth hijack 5 tanks or APCs.
Destroy 10 Blackwatch tanks, APCs or helicopters using a single hijacked tank or APC.
Simultaneously kill 2 Brawlers using a single Devastator.
20 or more kills with a single Hammerfist dive attack.
10 or more kills with a single Black Hole attack.
Complete the game.
Complete LABOR OF LOVE.
Complete all //BLACKNET dossiers.
Stealth Consume 50 Blackwatch troopers.
Weaponize 10 vehicles.
Mount a helicopter using Whipfist.
10 or more kills using a single Bio-Bomb.
Acquire 30 upgrades through Consumes.
Travel a half mile using only Wall Run, Glide, Jump and Air Dash.
Reach the highest point in the world.
Complete FALL FROM GRACE.
Karate kick a helicopter.
Destroy 5 vehicles using a Finisher.
Consume 10 //BLACKNET targets.
Acquire a Mutation in each of the 5 categories.
Counter enemy attacks 20 times using Shield.
Destroy a single Lair.
Acquire 10 upgrades through Consumes.
Acquire 5 Mutations.
Complete NATURAL SELECTION.
Deflect 5 missiles at enemies using Shield Block.
Trigger 50 alerts.
Complete a //BLACKNET operation.
5 consumes in 10 seconds or less.
Dismember a Brawler.
Acquire a Prototype Power.
Meet Father Guerra.
Complete RESURRECTION.
Complete MEET YOUR MAKER.