Here is the full list of all 43 Prototype 2 achievements. It takes around 20-25 hours to unlock all of the achievements on Windows.
Complete the game on HARD difficulty.
Fully upgrade Heller.
Find all BlackBoxes.
Destroy all Lairs.
Defeat all Field Ops teams.
Counter enemy attacks 20 times using Shield.
Spend at least 25 consecutive seconds in the air (helicopters don't count).
Travel a half mile using only Wall Run, Glide, Jump and Air Dash.
Acquire all 46 upgrades through Consumes.
Destroy 5 helicopters using Pack Leader.
Destroy a Strike Team in 15 seconds or less.
Stealth hijack 5 tanks or APCs.
Complete the game.
10 or more kills using a single Bio-Bomb.
Complete LABOR OF LOVE.
Complete all //BLACKNET dossiers.
Mount a helicopter using Whipfist.
Deflect 5 missiles at enemies using Shield Block.
Acquire 30 upgrades through Consumes.
Destroy 5 vehicles using a Finisher.
Reach the highest point in the world.
Complete FALL FROM GRACE.
Stealth Consume 50 Blackwatch troopers.
Weaponize 10 vehicles.
Simultaneously kill 2 Brawlers using a single Devastator.
Destroy 10 Blackwatch tanks, APCs or helicopters using a single hijacked tank or APC.
Consume 10 //BLACKNET targets.
Acquire a Mutation in each of the 5 categories.
10 or more kills with a single Black Hole attack.
Destroy a single Lair.
20 or more kills with a single Hammerfist dive attack.
Acquire 5 Mutations.
Acquire 10 upgrades through Consumes.
Complete NATURAL SELECTION.
Trigger 50 alerts.
Complete a //BLACKNET operation.
Dismember a Brawler.
5 consumes in 10 seconds or less.
Acquire a Prototype Power.
Meet Father Guerra.
Karate kick a helicopter.
Complete RESURRECTION.
Complete MEET YOUR MAKER.