Here is the full list of all 43 Prototype 2 achievements. It takes around 20-25 hours to unlock all of the achievements on Windows.
Complete the game on HARD difficulty.
Fully upgrade Heller.
Acquire all 46 upgrades through Consumes.
Destroy 5 helicopters using Pack Leader.
Travel a half mile using only Wall Run, Glide, Jump and Air Dash.
10 or more kills using a single Bio-Bomb.
Destroy 5 vehicles using a Finisher.
Weaponize 10 vehicles.
Destroy 10 Blackwatch tanks, APCs or helicopters using a single hijacked tank or APC.
Stealth hijack 5 tanks or APCs.
Destroy a Strike Team in 15 seconds or less.
Mount a helicopter using Whipfist.
Complete the game.
Complete LABOR OF LOVE.
Complete all //BLACKNET dossiers.
Defeat all Field Ops teams.
Destroy all Lairs.
Acquire 30 upgrades through Consumes.
Find all BlackBoxes.
Spend at least 25 consecutive seconds in the air (helicopters don't count).
Reach the highest point in the world.
Simultaneously kill 2 Brawlers using a single Devastator.
Complete FALL FROM GRACE.
20 or more kills with a single Hammerfist dive attack.
Consume 10 //BLACKNET targets.
Acquire a Mutation in each of the 5 categories.
10 or more kills with a single Black Hole attack.
Destroy a single Lair.
Acquire 10 upgrades through Consumes.
Complete NATURAL SELECTION.
Karate kick a helicopter.
Counter enemy attacks 20 times using Shield.
Deflect 5 missiles at enemies using Shield Block.
Acquire 5 Mutations.
Stealth Consume 50 Blackwatch troopers.
Trigger 50 alerts.
Dismember a Brawler.
Complete a //BLACKNET operation.
5 consumes in 10 seconds or less.
Acquire a Prototype Power.
Meet Father Guerra.
Complete RESURRECTION.
Complete MEET YOUR MAKER.