Here is the full list of all 43 Prototype 2 achievements. It takes around 20-25 hours to unlock all of the achievements on Windows.
Complete the game on HARD difficulty.
Destroy 10 Blackwatch tanks, APCs or helicopters using a single hijacked tank or APC.
Reach the highest point in the world.
Destroy 5 helicopters using Pack Leader.
Fully upgrade Heller.
Stealth hijack 5 tanks or APCs.
Karate kick a helicopter.
Travel a half mile using only Wall Run, Glide, Jump and Air Dash.
Destroy a Strike Team in 15 seconds or less.
Spend at least 25 consecutive seconds in the air (helicopters don't count).
Find all BlackBoxes.
Defeat all Field Ops teams.
Acquire all 46 upgrades through Consumes.
Destroy all Lairs.
Complete the game.
Complete LABOR OF LOVE.
Complete all //BLACKNET dossiers.
Mount a helicopter using Whipfist.
Acquire 30 upgrades through Consumes.
Simultaneously kill 2 Brawlers using a single Devastator.
10 or more kills using a single Bio-Bomb.
Complete FALL FROM GRACE.
20 or more kills with a single Hammerfist dive attack.
Destroy 5 vehicles using a Finisher.
Stealth Consume 50 Blackwatch troopers.
Consume 10 //BLACKNET targets.
Acquire a Mutation in each of the 5 categories.
Destroy a single Lair.
Acquire 10 upgrades through Consumes.
Weaponize 10 vehicles.
Complete NATURAL SELECTION.
Dismember a Brawler.
Counter enemy attacks 20 times using Shield.
Acquire 5 Mutations.
Deflect 5 missiles at enemies using Shield Block.
Trigger 50 alerts.
10 or more kills with a single Black Hole attack.
5 consumes in 10 seconds or less.
Complete a //BLACKNET operation.
Acquire a Prototype Power.
Meet Father Guerra.
Complete RESURRECTION.
Complete MEET YOUR MAKER.