Here is the full list of all 43 Prototype 2 achievements. It takes around 20-25 hours to unlock all of the achievements on Windows.
Fully upgrade Heller.
Destroy 5 helicopters using Pack Leader.
Destroy a Strike Team in 15 seconds or less.
Acquire all 46 upgrades through Consumes.
Simultaneously kill 2 Brawlers using a single Devastator.
Destroy 5 vehicles using a Finisher.
Weaponize 10 vehicles.
Complete the game.
Complete the game on HARD difficulty.
Complete LABOR OF LOVE.
Complete all //BLACKNET dossiers.
10 or more kills using a single Bio-Bomb.
Mount a helicopter using Whipfist.
Destroy all Lairs.
Acquire 30 upgrades through Consumes.
Find all BlackBoxes.
Defeat all Field Ops teams.
Spend at least 25 consecutive seconds in the air (helicopters don't count).
Reach the highest point in the world.
Complete FALL FROM GRACE.
20 or more kills with a single Hammerfist dive attack.
Destroy 10 Blackwatch tanks, APCs or helicopters using a single hijacked tank or APC.
Deflect 5 missiles at enemies using Shield Block.
Stealth hijack 5 tanks or APCs.
Consume 10 //BLACKNET targets.
Counter enemy attacks 20 times using Shield.
Acquire a Mutation in each of the 5 categories.
10 or more kills with a single Black Hole attack.
Acquire 10 upgrades through Consumes.
Stealth Consume 50 Blackwatch troopers.
Complete NATURAL SELECTION.
Karate kick a helicopter.
Destroy a single Lair.
Travel a half mile using only Wall Run, Glide, Jump and Air Dash.
Trigger 50 alerts.
Acquire 5 Mutations.
5 consumes in 10 seconds or less.
Complete a //BLACKNET operation.
Dismember a Brawler.
Acquire a Prototype Power.
Meet Father Guerra.
Complete RESURRECTION.
Complete MEET YOUR MAKER.