Here is the full list of all 43 Prototype 2 achievements. It takes around 20-25 hours to unlock all of the achievements on Windows.
Complete the game on HARD difficulty.
Fully upgrade Heller.
Destroy 5 vehicles using a Finisher.
Destroy all Lairs.
Find all BlackBoxes.
Defeat all Field Ops teams.
Complete all //BLACKNET dossiers.
Spend at least 25 consecutive seconds in the air (helicopters don't count).
Destroy 10 Blackwatch tanks, APCs or helicopters using a single hijacked tank or APC.
Acquire all 46 upgrades through Consumes.
Stealth hijack 5 tanks or APCs.
10 or more kills with a single Black Hole attack.
Destroy 5 helicopters using Pack Leader.
10 or more kills using a single Bio-Bomb.
20 or more kills with a single Hammerfist dive attack.
Weaponize 10 vehicles.
Mount a helicopter using Whipfist.
Complete the game.
Complete LABOR OF LOVE.
Travel a half mile using only Wall Run, Glide, Jump and Air Dash.
Acquire 30 upgrades through Consumes.
Reach the highest point in the world.
Complete FALL FROM GRACE.
Stealth Consume 50 Blackwatch troopers.
Consume 10 //BLACKNET targets.
Destroy a Strike Team in 15 seconds or less.
Counter enemy attacks 20 times using Shield.
Simultaneously kill 2 Brawlers using a single Devastator.
Acquire a Mutation in each of the 5 categories.
5 consumes in 10 seconds or less.
Destroy a single Lair.
Deflect 5 missiles at enemies using Shield Block.
Acquire 10 upgrades through Consumes.
Complete NATURAL SELECTION.
Karate kick a helicopter.
Trigger 50 alerts.
Acquire 5 Mutations.
Complete a //BLACKNET operation.
Dismember a Brawler.
Acquire a Prototype Power.
Meet Father Guerra.
Complete RESURRECTION.
Complete MEET YOUR MAKER.