Here is the full list of all 43 Prototype 2 achievements. It takes around 20-25 hours to unlock all of the achievements on Windows.
Fully upgrade Heller.
Acquire all 46 upgrades through Consumes.
Spend at least 25 consecutive seconds in the air (helicopters don't count).
Travel a half mile using only Wall Run, Glide, Jump and Air Dash.
10 or more kills using a single Bio-Bomb.
Destroy 5 helicopters using Pack Leader.
Mount a helicopter using Whipfist.
Reach the highest point in the world.
Destroy 5 vehicles using a Finisher.
Stealth hijack 5 tanks or APCs.
Weaponize 10 vehicles.
Karate kick a helicopter.
Destroy a Strike Team in 15 seconds or less.
Destroy 10 Blackwatch tanks, APCs or helicopters using a single hijacked tank or APC.
Complete the game.
Complete the game on HARD difficulty.
Complete LABOR OF LOVE.
Complete all //BLACKNET dossiers.
Acquire 30 upgrades through Consumes.
Destroy all Lairs.
Simultaneously kill 2 Brawlers using a single Devastator.
Find all BlackBoxes.
Defeat all Field Ops teams.
Complete FALL FROM GRACE.
Stealth Consume 50 Blackwatch troopers.
Consume 10 //BLACKNET targets.
20 or more kills with a single Hammerfist dive attack.
Acquire a Mutation in each of the 5 categories.
Acquire 10 upgrades through Consumes.
Destroy a single Lair.
10 or more kills with a single Black Hole attack.
Complete NATURAL SELECTION.
Deflect 5 missiles at enemies using Shield Block.
Counter enemy attacks 20 times using Shield.
5 consumes in 10 seconds or less.
Trigger 50 alerts.
Acquire 5 Mutations.
Dismember a Brawler.
Complete a //BLACKNET operation.
Acquire a Prototype Power.
Meet Father Guerra.
Complete RESURRECTION.
Complete MEET YOUR MAKER.