Here is the full list of all 43 Prototype 2 achievements. It takes around 20-25 hours to unlock all of the achievements on Windows.
Destroy a single Lair.
Complete NATURAL SELECTION.
Weaponize 10 vehicles.
Counter enemy attacks 20 times using Shield.
Stealth Consume 50 Blackwatch troopers.
Acquire 5 Mutations.
10 or more kills with a single Black Hole attack.
5 consumes in 10 seconds or less.
Deflect 5 missiles at enemies using Shield Block.
Trigger 50 alerts.
Complete a //BLACKNET operation.
Dismember a Brawler.
Acquire a Prototype Power.
Meet Father Guerra.
Complete RESURRECTION.
Complete MEET YOUR MAKER.
Complete FALL FROM GRACE.
Complete LABOR OF LOVE.
Complete the game.
Find all BlackBoxes.
Defeat all Field Ops teams.
Destroy a Strike Team in 15 seconds or less.
Simultaneously kill 2 Brawlers using a single Devastator.
Stealth hijack 5 tanks or APCs.
Destroy 10 Blackwatch tanks, APCs or helicopters using a single hijacked tank or APC.
Consume 10 //BLACKNET targets.
Acquire a Mutation in each of the 5 categories.
Travel a half mile using only Wall Run, Glide, Jump and Air Dash.
20 or more kills with a single Hammerfist dive attack.
10 or more kills using a single Bio-Bomb.
Destroy 5 helicopters using Pack Leader.
Karate kick a helicopter.
Mount a helicopter using Whipfist.
Destroy 5 vehicles using a Finisher.
Spend at least 25 consecutive seconds in the air (helicopters don't count).
Acquire 10 upgrades through Consumes.
Acquire 30 upgrades through Consumes.
Acquire all 46 upgrades through Consumes.
Reach the highest point in the world.
Destroy all Lairs.
Complete all //BLACKNET dossiers.
Fully upgrade Heller.
Complete the game on HARD difficulty.