Here is the full list of all 43 Prototype 2 achievements. It takes around 20-25 hours to unlock all of the achievements on Windows.
Fully upgrade Heller.
Destroy a Strike Team in 15 seconds or less.
Spend at least 25 consecutive seconds in the air (helicopters don't count).
Destroy 5 vehicles using a Finisher.
Destroy 10 Blackwatch tanks, APCs or helicopters using a single hijacked tank or APC.
Deflect 5 missiles at enemies using Shield Block.
Simultaneously kill 2 Brawlers using a single Devastator.
Karate kick a helicopter.
Destroy 5 helicopters using Pack Leader.
Weaponize 10 vehicles.
20 or more kills with a single Hammerfist dive attack.
10 or more kills with a single Black Hole attack.
Stealth Consume 50 Blackwatch troopers.
10 or more kills using a single Bio-Bomb.
Travel a half mile using only Wall Run, Glide, Jump and Air Dash.
Complete the game on HARD difficulty.
Complete the game.
Counter enemy attacks 20 times using Shield.
Complete LABOR OF LOVE.
Acquire all 46 upgrades through Consumes.
Complete all //BLACKNET dossiers.
Mount a helicopter using Whipfist.
Destroy all Lairs.
Defeat all Field Ops teams.
Reach the highest point in the world.
Acquire 30 upgrades through Consumes.
Find all BlackBoxes.
Complete FALL FROM GRACE.
Stealth hijack 5 tanks or APCs.
Consume 10 //BLACKNET targets.
Acquire a Mutation in each of the 5 categories.
Acquire 10 upgrades through Consumes.
Acquire 5 Mutations.
Destroy a single Lair.
Complete NATURAL SELECTION.
5 consumes in 10 seconds or less.
Trigger 50 alerts.
Dismember a Brawler.
Complete a //BLACKNET operation.
Acquire a Prototype Power.
Meet Father Guerra.
Complete RESURRECTION.
Complete MEET YOUR MAKER.