Here is the full list of all 43 Prototype 2 achievements. It takes around 20-25 hours to unlock all of the achievements on Windows.
Fully upgrade Heller.
20 or more kills with a single Hammerfist dive attack.
10 or more kills with a single Black Hole attack.
Destroy 5 vehicles using a Finisher.
Travel a half mile using only Wall Run, Glide, Jump and Air Dash.
Destroy 5 helicopters using Pack Leader.
Spend at least 25 consecutive seconds in the air (helicopters don't count).
Reach the highest point in the world.
Find all BlackBoxes.
Defeat all Field Ops teams.
Destroy 10 Blackwatch tanks, APCs or helicopters using a single hijacked tank or APC.
Destroy all Lairs.
10 or more kills using a single Bio-Bomb.
Acquire all 46 upgrades through Consumes.
Destroy a Strike Team in 15 seconds or less.
Complete all //BLACKNET dossiers.
Mount a helicopter using Whipfist.
Complete the game.
Complete the game on HARD difficulty.
Simultaneously kill 2 Brawlers using a single Devastator.
Complete LABOR OF LOVE.
Acquire 30 upgrades through Consumes.
Complete FALL FROM GRACE.
Karate kick a helicopter.
Acquire a Mutation in each of the 5 categories.
Stealth hijack 5 tanks or APCs.
Consume 10 //BLACKNET targets.
Stealth Consume 50 Blackwatch troopers.
Weaponize 10 vehicles.
Acquire 5 Mutations.
Destroy a single Lair.
Acquire 10 upgrades through Consumes.
Complete NATURAL SELECTION.
Counter enemy attacks 20 times using Shield.
Deflect 5 missiles at enemies using Shield Block.
Trigger 50 alerts.
5 consumes in 10 seconds or less.
Complete a //BLACKNET operation.
Dismember a Brawler.
Acquire a Prototype Power.
Meet Father Guerra.
Complete RESURRECTION.
Complete MEET YOUR MAKER.