Here is the full list of all 65 Defense Grid 2 achievements.
Complete the single player campaign in Story Mode.
Earn a silver medal (or better) on all missions in the Story mode.
Earn a gold medal on every mission in Story mode.
Win a Gold medal on mission 19 without using the Command Shuttle.
Build 100 Gun towers.
Win a chapter 4 (or later) mission with level 3 towers only and no selling.
Kill 10,000 aliens.
Using only Cannon towers, Win any chapter 4 (or later) mission.
Survive 100 waves on any Super Grinder challenge mode.
Build 100 Cannon towers.
Survive 100 waves on Grinder challenge mode on any mission.
Use the Precision Targeting Special Weapon (Rear Admiral Phillips).
Build every tower and every upgrade for each tower.
Build 1 of each tower type in any single mission.
Build and fully upgrade each tower type in one mission.
Beat a Chapter 4 mission or higher with zero cores captured.
Win a mission with at least 10,000 resources remaining.
Use the Temporal Cannon Special Weapon (Colonel Rissler).
Enable a Tower Augmentation item on any tower.
Sell 10 towers or more in a single mission.
Inspect 10 aliens.
Kill an alien boss creature. (Juggernaut, Rumbler, Turtle, or Crasher)
Build 20 towers of any type in one mission.
Use the Resource Reinforcement Special Weapon (Professor Briel).
Sell 10 towers.
Use the Tower Overcharge Special Weapon (Advisor Zacara).
Use the speed up control at 3x for a total of 60 seconds in any mission.
Finish all the missions in Chapter 1 in Story Mode.
Kill 1000 aliens.
Win any mission without selling any towers.
Win a mission with at least 5,000 resources remaining.
Recover a loose core.
Kill an alien carrying a power core.
Save a core that is less than 10 seconds away from the map's exit point.
Earn a silver (or better) medal.
Earn a Gold Medal.
Use the Reload Checkpoint option.
Kill 100 aliens.
Kill 1 alien.
Win a mission with at least 1,000 resources remaining.
Upgrade a level 1 tower to a level 2 tower.
Use the Orbital Laser Special Weapon (General Cai).
Earn Bronze on a Single Player mission.
Kill 50,000 aliens.
Build 50 towers of any type in one mission.
Use the reload checkpoint option five times in a single mission.
Build 100 Inferno towers.
Build 100 Laser towers.
Build 100 Temporal towers.
Build 100 Meteor towers.
Build 100 Tesla towers.
Build 100 Missile towers.
Build 100 Concussion towers.
Build 100 Boost towers.
Use the Core Teleport special weapon (Professor Taylor).
Using only Gun towers, Win any chapter 4 (or later) mission.
Using only Inferno towers, Win any chapter 4 (or later) mission.
Using only level 1 towers, Win any Chapter 4 (or later) mission.
Earn 100 Gold Medals on any missions.
Enable a Tower Augmentation Item on 10 Towers.
Use the command shuttle to move 6 map sections in Mission 6.
Play a Competitive Multiplayer mission.
Earn a Victory in a DG Fighter Multiplayer mission.
Earn Bronze in a Co-Op Multiplayer mission.
Earn Gold in a Co-Op Multiplayer mission.