Here is the full list of all 65 Defense Grid 2 achievements.
Using only level 1 towers, Win any Chapter 4 (or later) mission.
Use the command shuttle to move 6 map sections in Mission 6.
Use the Precision Targeting Special Weapon (Rear Admiral Phillips).
Using only Inferno towers, Win any chapter 4 (or later) mission.
Use the Tower Overcharge Special Weapon (Advisor Zacara).
Using only Cannon towers, Win any chapter 4 (or later) mission.
Use the Temporal Cannon Special Weapon (Colonel Rissler).
Sell 10 towers or more in a single mission.
Build 100 Concussion towers.
Using only Gun towers, Win any chapter 4 (or later) mission.
Build 100 Temporal towers.
Build 100 Cannon towers.
Build 50 towers of any type in one mission.
Build 100 Meteor towers.
Kill 50,000 aliens.
Build 100 Missile towers.
Build 100 Laser towers.
Use the Resource Reinforcement Special Weapon (Professor Briel).
Earn a gold medal on every mission in Story mode.
Survive 100 waves on any Super Grinder challenge mode.
Build 100 Boost towers.
Build every tower and every upgrade for each tower.
Build 1 of each tower type in any single mission.
Build and fully upgrade each tower type in one mission.
Enable a Tower Augmentation Item on 10 Towers.
Build 100 Inferno towers.
Kill 10,000 aliens.
Survive 100 waves on Grinder challenge mode on any mission.
Complete the single player campaign in Story Mode.
Earn a silver medal (or better) on all missions in the Story mode.
Win a Gold medal on mission 19 without using the Command Shuttle.
Win a mission with at least 10,000 resources remaining.
Sell 10 towers.
Build 100 Gun towers.
Win a chapter 4 (or later) mission with level 3 towers only and no selling.
Beat a Chapter 4 mission or higher with zero cores captured.
Inspect 10 aliens.
Win a mission with at least 5,000 resources remaining.
Kill an alien boss creature. (Juggernaut, Rumbler, Turtle, or Crasher)
Use the speed up control at 3x for a total of 60 seconds in any mission.
Kill 1000 aliens.
Build 20 towers of any type in one mission.
Finish all the missions in Chapter 1 in Story Mode.
Enable a Tower Augmentation item on any tower.
Recover a loose core.
Kill an alien carrying a power core.
Use the Reload Checkpoint option.
Use the reload checkpoint option five times in a single mission.
Save a core that is less than 10 seconds away from the map's exit point.
Kill 100 aliens.
Earn a silver (or better) medal.
Earn a Gold Medal.
Win a mission with at least 1,000 resources remaining.
Upgrade a level 1 tower to a level 2 tower.
Use the Orbital Laser Special Weapon (General Cai).
Win any mission without selling any towers.
Earn Bronze on a Single Player mission.
Kill 1 alien.
Build 100 Tesla towers.
Use the Core Teleport special weapon (Professor Taylor).
Earn 100 Gold Medals on any missions.
Play a Competitive Multiplayer mission.
Earn a Victory in a DG Fighter Multiplayer mission.
Earn Bronze in a Co-Op Multiplayer mission.
Earn Gold in a Co-Op Multiplayer mission.