While this may seem tricky, it becomes fairly easy to achieve once you grasp the concept that shield hits are still considered as damage taken at the time of writing this guide.
I would suggest starting with the hand crossbow and the angel wing, and then moving up with the crosstornado (unlocked via the vault) making sure that both of them touch the angel wing. Try to fill all small 2x1 the empty spaces with recovery increasing items as they will boost the attack speed and the damage thanks to the angel wing.
When you have more space, try to fit in another hand crossbow touching at least the angel wing to boost the blessed and piercing sets. Automatic crossbow and scattershot crossbow are also very good options if ou have the space. Once you have 4-5 weapons you should be more than ok to easily complete the challenge, the damage output and the piercing+spread will ensure that even elites are taken down before they can harm you, be sure to dash appropriately when there is danger.