If you remember where the Shit Pickles cameo locations were in the original version of The Angry Video Game Nerd Adventures. Well, they're still in those locations in this version of the game. Just remember after triggering Shit Pickles at each location to get to a check point.
Thus, dying no longer prevents you from getting that cameo as a part of getting 100% completion process. You don't have to go far off the path to do these. Otherwise, I actually don't have much else to tell you.