This DLC's story takes place after the end of the main game, so it's recommended that you don't start it until you've finished at least the story.
Enter the Dominatrix: Save the Planet
This quest starts on the ship. After the main story, Jane Valderama will interview the Saints about a cut story that existed before the development of Saints Row IV itself. After Zinyak explains that he was too good to just throw away as a character.
When the first cut mission starts, grab one of three super-heavy weapons and head to the roof with it. Parachute down with Josh and defeat all of the Zin in front of the Saints' building. After taking out about three waves of enemies, you'll get an unfinished cutscene of Josh fighting off aliens - from his memory.
After the cutscene, drive the Gatmobile to the mayor's office so the mayor can help you figure out where Zinyak is. Pierce will offer to ride with you there in his tank; take control of it and defeat all of Zinyak's tanks so you can reach Zinyak. The achievement related to this quest requires you to defeat Zinyak in under five minutes. Shoot at him until you're able to start a quicktime event on him to finish him off.
Enter the Dominatrix: Meet the Dominatrix
Note: To get the DLC's weapon-based achievements much faster, consider obtaining the upgrade for infinite special ammo before starting this quest.
Note: There's an achievement for finishing this quest without dying. Restart the quest or do it on an easier difficulty if you die at any point.
On the ship, select the next quest so you can start the next segment of Enter the Dominatrix. Jane will first interview Donnie, a character from previous adventures. Kinzie explains that Zinyak's simulation AI took over after his death and took the form of a Dominatrix. Donnie was once an important figure in the game until he got cut, and the mission places you right after your training with him.
Jump over to the next location and fight off the Dominatrix until she disappears, which results in her kidnapping both Pierce and Shaundi. Don't go anywhere just yet, because this is the perfect place to take care of the three weapon achievements. You should have one from the previous quest in your inventory. Every half minute or so, a new set of enemies will pull in to fight you. This is how you're going to have to rack up the required kills for these weapons. You can switch weapons in the weapon shop right in this area.
Donnie will head off to save Shaundi, so you get to go after Pierce. When you arrive on-scene, the Dominatrix will attack. Fight her off and then do the same to her troops, then continue repeating this cycle so you can save Pierce. After saving him, Donnie will ask you to save Shaundi for him (as well as himself). Defend yourself against the Dominatrix and her people, triggering Kinzie to explain that she has a plan. Meet up with her and fight the Dominatrix once again until she's dizzy, then activate a node to further isolate her into one body. Repeat this until she's completely lost her ability to duplicate, ending this quest.
Enter the Dominatrix: At the Races
Note: For an easy time at this quest's related achievement, consider highly upgrading the disintegrator and/or thumpgun before starting.
You and Kinzie have found the Dominatrix in a sex club. Talk to her second-in-command, Dom, and he'll tell you to put the furries back in their cages away from everyone else, where they belong. After you've done this, Dom will tell you to please a client. It's none other than Zimos, who's willing to cooperate for your sake.
After this, Dom will tell you to eliminate the chariot champions around the club. After that, Dom will reveal that he used you to eliminate the competition for himself, now the greatest chariot racer of the club. Kill Dom's subordinates and then Dom himself, leading to a cut screen that puts you at the start of a chariot race. You'll want to kill every single opposing chariot in this race for an achievement. Some upgrades won't carry over, like if you've got the infinite ammo upgrade for the disintegrator's weapon type, but many still do. You can alternatively use dual SMGs, which will retain their infinite ammo in this quest. It shouldn't be too difficult to defeat them all.
The quest ends after the race.
Enter the Dominatrix: Pop His Top
After rescuing Zimos, the Dominatrix will order Paul (the giant Saints Flow mascot) to attack, with the game skipping some apparently terrible gameplay to put you right inside Paul's mouth. This mission's achievement asks you to blow up every green polyp in Paul's body using the ship's lasers. It'll be a while before you actually see one, but you'll know when you do. Polyps are big, spherical, and green, and don't take much to be destroyed. If you miss a single polyp, restart the quest (it's incredibly short). The quest ends once you leave Paul's head.
Enter the Dominatrix: Escape the Dominatrix
You and Zimos will be attacked by a supergimp when the mission starts. Defeat him, then meet up with Shaundi and help her take care of the gimps swarming her. Donnie will ask you to do the same thing for him, but the Dominatrix will spawn herself in during this part. After being defeated, she'll reboot the DLC and everything will be reset aside from Zimos. Take the elevator down and you'll immediately start a fight with the Dominatrix.
Fight the Dominatrix as you would any powered-up enemy. After taking about a third of her total health away, she'll disappear and send tanks towards you. After two thirds of her health are gone, she'll drop VTOLs at you. Deplete her of her last third of health and you'll finally defeat her.
After she's been defeated, Pierce will reveal that he brought in some allies that hate the Zin as much as you do. You'll automatically travel with your new friends towards the simulation's exit.
After completing the DLC, you'll unlock a homie named Raptor Ned, a prehistoric ancestor of Saints Row 1's Chicken Ned. Spend at least half an hour with him for an achievement.
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