Here is the full list of all 20 Please Leave Me Alone, I Need to Poop achievements.
Fail the minigames and get a Game Over.
Fail the presentation and get fired.
Beat the minigames and make it to the bathroom for the first time.
Pass the presentation for the first time.
Pass every presentation.
Get a perfect score on every presentation.
Unlock Run & Stunner in arcade mode.
Punch every single coworker in Run & Stunner.
Unlock Hallway Pitch Party in arcade mode.
Win Hallway Pitch Party with 4 or fewer projectiles.
Unlock Stall Buster in arcade mode.
Beat Stall Buster with zero misses.
Unlock RPS in arcade mode.
Win RPS after losing the first round.
Unlock Perv Poker in arcade mode.
Successfully poke the Perv 3 times in a row.
Unlock Seat Wiper in arcade mode.
Win after puking 3 times in Seat Wiper.
Unlock all minigames in arcade mode.
Unlock all other achievements.