Here is the full list of all 24 Attack of the Karens achievements.
Defeat Cassie with no Kushions Active
Defeat Marva with no Kushions Active
Defeat Tiffany with no Kushions active
Defeat Jordan with no Kushions active
Defeat 100 enemies
Defeat 1000 enemies
Defeat 10,000 enemies
Amass 600 Modules in your bank
Unlock the Module Cannon
Unlock all four health upgrades at the K-Scan shop
Unlock all four fire rate upgrades at the K-Scan shop
Unlock all four movement speed upgrades at the K-Scan shop
Unlock all four blaster damage upgrades at the K-Scan shop
Complete the game with three or more Kurses active and no Kushions
Complete the game with three or more Kushions active and no Kurses
Complete the game with all Kushions and no Kurses active
Complete the game with all Kurses and no Kushions active
Complete the game with all Kurses and all Kushions active
Defeat Cassie when she appears on the fourth level with no Kusions active
Defeat Marva when she appears on the fourth level with no Kushions active
Defeat Tiffany when she appears on the fourth level with no Kushions active
Defeat Jordan when she appears on the fourth level with no Kushions active
Defeat Amanda's demon form with no Kushions Active
Purchase your first upgrade at the module shop.