Here is the full list of all 121 The Madness of Little Emma achievements.
Unlock fifth ending
Unlock Marah
Unlock third ending
Kill April
Kill Manless Face as Amelia
Unlock second ending
Get very lucky
Kill Sinister Mask
Kill all bosses in episode 3
Reach The Riddle
Kill Manless Face
Kill a shopkeeper
Kill 4 Seasons
Kill Summer
Kill Winter
Destroy a turnip
Complete episode 1 without collecting hearts and healing herbs
Kill Autumn
Kill Spring
Unlock first ending
Get really insane!
Kill Meat Bag
Kill the fat man
Kill all bosses in episode 2
Get very unlucky
Reach Misery
Buy 5 items in one playthrough
Kill Entozoon
Have only 1 heart container
Unlock Lucretia
Kill all bosses in episode 1
Kill Liquid Sisters
Unlock Elizabeth
Kill Alice
Unlock Amelia
Find Love Burrow
Kill Red Viper
Find a red chest
Collect 5 health bonuses in one game
Kill Green Viper
Kill Mask
Reach Undergrounds
Reach Den
Kill a boss
Kill Haunt
Find a secret
Die
Unlock final ending
Kill all bosses in episode 4
Find everything
Complete ending 4 with clean mind all the time
Unlock every other achievement
Complete episode 2 without collecting hearts and healing herbs
Complete episode 3 without collecting hearts and healing herbs
Complete episode 4 without collecting hearts and healing herbs
Kill Eidolon
Kill Spirit
Find all Love Items
Unlock sixth ending
Unlock Chloe
Complete Arena as Emma
Complete Arena
Complete Arena as Lucretia
Complete Arena as Elizabeth
Complete Arena as Amelia
Complete Arena as Marah
Complete Arena as Chloe