Here is the full list of all 121 The Madness of Little Emma achievements.
Unlock first ending
Kill Meat Bag
Kill all bosses in episode 2
Kill Entozoon
Get very unlucky
Kill Red Viper
Have only 1 heart container
Reach Misery
Kill the fat man
Unlock Amelia
Find Love Burrow
Kill Alice
Unlock Lucretia
Buy 5 items in one playthrough
Kill all bosses in episode 1
Collect 5 health bonuses in one game
Find a secret
Unlock Elizabeth
Kill Liquid Sisters
Reach Undergrounds
Find a red chest
Kill Haunt
Die
Reach Den
Kill Green Viper
Kill a boss
Kill Mask
Reach The Riddle
Unlock second ending
Unlock third ending
Unlock final ending
Kill all bosses in episode 3
Kill all bosses in episode 4
Kill 4 Seasons
Kill April
Find everything
Complete ending 4 with clean mind all the time
Get really insane!
Get very lucky
Unlock every other achievement
Complete episode 1 without collecting hearts and healing herbs
Complete episode 2 without collecting hearts and healing herbs
Complete episode 3 without collecting hearts and healing herbs
Complete episode 4 without collecting hearts and healing herbs
Destroy a turnip
Kill a shopkeeper
Kill Sinister Mask
Kill Manless Face
Kill Eidolon
Kill Spirit
Kill Summer
Kill Autumn
Kill Winter
Kill Spring
Find all Love Items
Unlock fifth ending
Unlock sixth ending
Kill Manless Face as Amelia
Unlock Marah
Unlock Chloe
Complete Arena as Emma
Complete Arena
Complete Arena as Lucretia
Complete Arena as Elizabeth
Complete Arena as Amelia
Complete Arena as Marah
Complete Arena as Chloe