Here is the full list of all 121 The Madness of Little Emma achievements.
Complete episode 2 without collecting hearts and healing herbs
Complete Arena as Chloe
Complete episode 1 without collecting hearts and healing herbs
Unlock Chloe
Complete Arena as Emma
Complete Arena
Complete episode 4 without collecting hearts and healing herbs
Unlock fifth ending
Kill all bosses in episode 3
Kill Meat Bag
Unlock second ending
Kill Eidolon
Reach The Riddle
Get really insane!
Kill 4 Seasons
Kill Summer
Get very lucky
Kill Autumn
Kill Winter
Kill Spring
Unlock first ending
Kill Manless Face
Get very unlucky
Kill a shopkeeper
Buy 5 items in one playthrough
Kill Sinister Mask
Destroy a turnip
Have only 1 heart container
Kill Alice
Kill all bosses in episode 2
Unlock Lucretia
Unlock Elizabeth
Kill the fat man
Collect 5 health bonuses in one game
Reach Misery
Kill Entozoon
Kill Red Viper
Find a red chest
Find Love Burrow
Unlock Amelia
Kill all bosses in episode 1
Kill Mask
Reach Den
Reach Undergrounds
Kill Green Viper
Kill a boss
Find a secret
Die
Kill Haunt
Kill Liquid Sisters
Unlock third ending
Unlock final ending
Kill all bosses in episode 4
Kill April
Find everything
Complete ending 4 with clean mind all the time
Unlock every other achievement
Complete episode 3 without collecting hearts and healing herbs
Kill Spirit
Find all Love Items
Unlock sixth ending
Kill Manless Face as Amelia
Unlock Marah
Complete Arena as Lucretia
Complete Arena as Elizabeth
Complete Arena as Amelia
Complete Arena as Marah