Here is the full list of all 121 The Madness of Little Emma achievements.
Kill Autumn
Kill all bosses in episode 1
Kill Haunt
Get very unlucky
Unlock first ending
Kill Manless Face
Get really insane!
Buy 5 items in one playthrough
Kill Meat Bag
Unlock Lucretia
Reach Misery
Destroy a turnip
Kill Entozoon
Unlock Elizabeth
Kill Mask
Reach Undergrounds
Kill Alice
Reach Den
Unlock Amelia
Find Love Burrow
Find a secret
Collect 5 health bonuses in one game
Kill Green Viper
Die
Kill a boss
Kill Liquid Sisters
Reach The Riddle
Unlock second ending
Unlock third ending
Unlock final ending
Kill all bosses in episode 2
Kill all bosses in episode 3
Kill all bosses in episode 4
Kill 4 Seasons
Kill April
Find everything
Find a red chest
Complete ending 4 with clean mind all the time
Get very lucky
Unlock every other achievement
Complete episode 1 without collecting hearts and healing herbs
Complete episode 2 without collecting hearts and healing herbs
Complete episode 3 without collecting hearts and healing herbs
Complete episode 4 without collecting hearts and healing herbs
Kill a shopkeeper
Have only 1 heart container
Kill the fat man
Kill Red Viper
Kill Sinister Mask
Kill Eidolon
Kill Spirit
Kill Summer
Kill Winter
Kill Spring
Find all Love Items
Unlock fifth ending
Unlock sixth ending
Kill Manless Face as Amelia
Unlock Marah
Unlock Chloe
Complete Arena as Emma
Complete Arena
Complete Arena as Lucretia
Complete Arena as Elizabeth
Complete Arena as Amelia
Complete Arena as Marah
Complete Arena as Chloe