Here is the full list of all 25 The Enchanted Cave 2 achievements.
Equip an artifact in every equipment slot
Save three people
Save two people
Complete Green Goo's Quest
Transmute an item
Save one person
Complete the crafting section of the skill tree
Completely fill all sections of the museum
Defeat the final boss
Defeat the sorcerer
Completely fill one equipment section of the museum
Complete the magic section of the skill tree
Craft 75 total potions
Reach character level 25
Defeat the Yeti
Discover 10 secret areas
Complete the combat section of the skill tree
Craft 15 total potions
Completely clear one floor of all enemies and loot
Successfully escape the cave with an artifact
Complete the Monster's Lair Challenge
Complete the Labyrinth Challenge
Complete the main game in a single run
Complete a New Game +