Here is the full list of all 25 The Enchanted Cave 2 achievements.
Complete Green Goo's Quest
Complete the Labyrinth Challenge
Complete the Monster's Lair Challenge
Completely fill all sections of the museum
Complete a New Game +
Complete the main game in a single run
Complete the crafting section of the skill tree
Complete the magic section of the skill tree
Transmute an item
Completely fill one equipment section of the museum
Craft 75 total potions
Defeat the final boss
Defeat the sorcerer
Craft 15 total potions
Reach character level 25
Defeat the Yeti
Save three people
Complete the combat section of the skill tree
Save two people
Discover 10 secret areas
Equip an artifact in every equipment slot
Save one person
Completely clear one floor of all enemies and loot
Successfully escape the cave with an artifact