Here is the full list of all 25 The Enchanted Cave 2 achievements.
Complete the Labyrinth Challenge
Completely fill all sections of the museum
Complete a New Game +
Completely fill one equipment section of the museum
Complete Green Goo's Quest
Complete the main game in a single run
Complete the Monster's Lair Challenge
Discover 10 secret areas
Defeat the final boss
Defeat the sorcerer
Complete the magic section of the skill tree
Craft 75 total potions
Complete the crafting section of the skill tree
Reach character level 25
Craft 15 total potions
Defeat the Yeti
Complete the combat section of the skill tree
Save three people
Save two people
Successfully escape the cave with an artifact
Equip an artifact in every equipment slot
Transmute an item
Save one person
Completely clear one floor of all enemies and loot