Here is the full list of all 25 The Enchanted Cave 2 achievements.
Complete the main game in a single run
Complete Green Goo's Quest
Complete the Labyrinth Challenge
Complete the Monster's Lair Challenge
Complete the crafting section of the skill tree
Complete a New Game +
Completely fill all sections of the museum
Completely fill one equipment section of the museum
Complete the magic section of the skill tree
Transmute an item
Defeat the final boss
Craft 75 total potions
Defeat the sorcerer
Reach character level 25
Craft 15 total potions
Defeat the Yeti
Save three people
Equip an artifact in every equipment slot
Save two people
Discover 10 secret areas
Complete the combat section of the skill tree
Save one person
Successfully escape the cave with an artifact
Completely clear one floor of all enemies and loot