Here is the full list of all 25 The Enchanted Cave 2 achievements.
Complete Green Goo's Quest
Complete a New Game +
Complete the Labyrinth Challenge
Complete the Monster's Lair Challenge
Transmute an item
Complete the main game in a single run
Save three people
Save two people
Save one person
Equip an artifact in every equipment slot
Completely fill all sections of the museum
Completely fill one equipment section of the museum
Complete the magic section of the skill tree
Complete the crafting section of the skill tree
Craft 75 total potions
Defeat the final boss
Reach character level 25
Defeat the sorcerer
Defeat the Yeti
Craft 15 total potions
Complete the combat section of the skill tree
Discover 10 secret areas
Completely clear one floor of all enemies and loot
Successfully escape the cave with an artifact