Here is the full list of all 25 The Enchanted Cave 2 achievements.
Save two people
Transmute an item
Equip an artifact in every equipment slot
Save one person
Complete the crafting section of the skill tree
Craft 75 total potions
Complete the magic section of the skill tree
Defeat the final boss
Completely fill all sections of the museum
Completely fill one equipment section of the museum
Defeat the sorcerer
Craft 15 total potions
Reach character level 25
Defeat the Yeti
Complete the combat section of the skill tree
Discover 10 secret areas
Successfully escape the cave with an artifact
Completely clear one floor of all enemies and loot
Complete the Monster's Lair Challenge
Complete the Labyrinth Challenge
Complete Green Goo's Quest
Save three people
Complete the main game in a single run
Complete a New Game +