Here is the full list of all 25 The Enchanted Cave 2 achievements.
Complete the crafting section of the skill tree
Complete a New Game +
Complete the main game in a single run
Defeat the final boss
Completely fill all sections of the museum
Completely fill one equipment section of the museum
Complete the magic section of the skill tree
Defeat the sorcerer
Craft 75 total potions
Transmute an item
Reach character level 25
Defeat the Yeti
Complete the combat section of the skill tree
Save three people
Equip an artifact in every equipment slot
Save two people
Discover 10 secret areas
Save one person
Craft 15 total potions
Completely clear one floor of all enemies and loot
Successfully escape the cave with an artifact
Complete the Monster's Lair Challenge
Complete the Labyrinth Challenge
Complete Green Goo's Quest