Full list of all 99 The Binding of Isaac achievements. It takes around 200 hours to unlock all of the achievements in the base game on Windows.
The base game contains 52 achievements, and there are 2 DLC packs containing 47 achievements.
100% the game
ive lost my head one too many times...
You defeated Steven!
Defeat all bosses in the caves
Dirty needles... eww
Make a Super Meat Boy!
Complete Sheol with Cain
Complete the full game with ???
Give mom a taste of her own medicine!
Call death upon all of them!
Complete the womb with Eve
Complete Sheol with Eve
Complete Sheol with ???
Complete the full game with Judas
Complete the full game with Maggy
Destroy the 7 Sins!
You defeated Gish!
Complete Sheol with Judas
Complete Sheol with Maggy
Complete the full game 8 times
Complete the full game 9 times
Complete the full game with Cain
Kids shouldnt play with matches...
stay out of moms things!
i lost mine in the arcade...
Complete the full game 10 times
Complete the full game 6 times
Complete the full game 7 times
Kids shouldnt play with dead things...
Complete the caves without taking damage
Complete the depths without taking damage
Complete the womb without taking damage
Complete the full game 4 times
Complete the full game 5 times
Defeat all bosses in the basement
You defeated C.H.A.D.!
Make 2 deals with the devil in one play through
Find Krampus in Satans room for a gift!
Complete the full game 2 times
Complete the full game 3 times
Defeat all bosses in the depths
mom needs her pills! donate blood.
Collect 50+ pennies in one play through
Complete Sheol with Isaac
you dont wanna know where this bean has been...
Complete the basement without taking damage
i like to break things...
Collect 7+ container hearts in one play through
Complete the full game
Complete the basement
Complete the Caves
kill mom...
???
Complete the final chapter with Eve
Complete the final chapter with Samson
Complete the final chapter with Maggy
Complete the final chapter with ???
Complete the final chapter with Judas
Kill moms heart with Samson
Kill Satan with Samson
Complete the final chapter with Cain
Complete the final chapter with Isaac
Complete Challenge 7
Complete Challenge 9
Complete Challenge 3
Complete Challenge 1
Complete Challenge 2
Complete Challenge 4
Complete Challenge 5
Complete Challenge 8
Kill mom but pass on 2 treasure room items
Complete Challenge 6
100% the game and hardmode (get all the achievements)
Beat the game as Isaac in Hardmode
Beat the game as all characters in Hardmode.
Beat the game as Eve in Hardmode
Beat the game as Judas in Hardmode
Beat the game as Samson in Hardmode
Beat the game as Cain in Hardmode
Beat the game as Magdalen in Hardmode
Beat the game as ??? in Hardmode, and good luck!
Beat the Game in Hardmode!
Beat the boss in the Cathedral in Hardmode
Beat Mom in Hardmode
Beat Moms Heart in Hardmode
Beat Satan in Hardmode
Gain 7 Health upgrades from Eternal Hearts