Full list of all 99 The Binding of Isaac achievements. It takes around 200 hours to unlock all of the achievements in the base game on Windows.
The base game contains 52 achievements, and there are 2 DLC packs containing 47 achievements.
100% the game
Complete Sheol with Maggy
Complete Sheol with Judas
Complete Sheol with ???
Complete Sheol with Cain
Complete the womb without taking damage
Complete the depths without taking damage
Complete the womb with Eve
Complete Sheol with Eve
Make a Super Meat Boy!
Complete the caves without taking damage
ive lost my head one too many times...
Complete Sheol with Isaac
Find Krampus in Satans room for a gift!
Make 2 deals with the devil in one play through
You defeated Gish!
stay out of moms things!
Give mom a taste of her own medicine!
You defeated C.H.A.D.!
You defeated Steven!
Complete the full game with ???
Complete the full game 10 times
Complete the full game 9 times
Complete the full game 8 times
Complete the full game 7 times
Defeat all bosses in the depths
mom needs her pills! donate blood.
Complete the full game 6 times
Complete the full game 5 times
Complete the full game 4 times
Complete the full game 3 times
Complete the full game with Judas
i lost mine in the arcade...
Defeat all bosses in the caves
Complete the full game 2 times
Complete the full game with Cain
Destroy the 7 Sins!
Kids shouldnt play with dead things...
Complete the full game
Complete the full game with Maggy
Kids shouldnt play with matches...
Collect 50+ pennies in one play through
kill mom...
Complete the basement without taking damage
Complete the basement
Defeat all bosses in the basement
Complete the Caves
Dirty needles... eww
you dont wanna know where this bean has been...
i like to break things...
Collect 7+ container hearts in one play through
Call death upon all of them!
???
Complete the final chapter with Eve
Kill Satan with Samson
Complete the final chapter with Judas
Complete the final chapter with Cain
Complete the final chapter with Maggy
Complete the final chapter with ???
Complete Challenge 9
Complete Challenge 8
Kill moms heart with Samson
Complete the final chapter with Samson
Complete Challenge 4
Complete Challenge 5
Complete Challenge 6
Complete Challenge 3
Complete Challenge 2
Complete Challenge 7
Kill mom but pass on 2 treasure room items
Complete Challenge 1
Complete the final chapter with Isaac
Beat Satan in Hardmode
Beat the game as Isaac in Hardmode
Beat the game as Cain in Hardmode
Beat the game as Judas in Hardmode
Beat the game as all characters in Hardmode.
100% the game and hardmode (get all the achievements)
Beat the game as Samson in Hardmode
Gain 7 Health upgrades from Eternal Hearts
Beat the game as Eve in Hardmode
Beat the game as Magdalen in Hardmode
Beat Mom in Hardmode
Beat Moms Heart in Hardmode
Beat the boss in the Cathedral in Hardmode
Beat the Game in Hardmode!
Beat the game as ??? in Hardmode, and good luck!