Full list of all 99 The Binding of Isaac achievements. It takes around 200 hours to unlock all of the achievements in the base game on Windows.
The base game contains 52 achievements, and there are 2 DLC packs containing 47 achievements.
Dirty needles... eww
Complete Sheol with Judas
Complete the womb without taking damage
Complete the depths without taking damage
100% the game
Complete the caves without taking damage
Complete Sheol with ???
Complete the womb with Eve
Complete Sheol with Eve
Complete the full game with Maggy
Complete Sheol with Maggy
stay out of moms things!
Complete the full game with Judas
Complete Sheol with Cain
You defeated Gish!
You defeated Steven!
ive lost my head one too many times...
Complete Sheol with Isaac
Complete the full game 10 times
Complete the full game 9 times
Complete the full game with ???
Complete the full game 8 times
i lost mine in the arcade...
Complete the full game 7 times
Make a Super Meat Boy!
Complete the full game 6 times
Call death upon all of them!
Complete the basement without taking damage
Complete the full game 5 times
mom needs her pills! donate blood.
Complete the full game 4 times
Complete the full game 3 times
Defeat all bosses in the caves
Defeat all bosses in the depths
Complete the full game 2 times
Complete the full game with Cain
Destroy the 7 Sins!
Make 2 deals with the devil in one play through
Complete the full game
Kids shouldnt play with dead things...
Collect 7+ container hearts in one play through
Find Krampus in Satans room for a gift!
You defeated C.H.A.D.!
Kids shouldnt play with matches...
Collect 50+ pennies in one play through
Complete the Caves
kill mom...
Give mom a taste of her own medicine!
Defeat all bosses in the basement
you dont wanna know where this bean has been...
i like to break things...
Complete the basement
Kill Satan with Samson
Complete Challenge 8
Complete Challenge 5
Kill moms heart with Samson
Complete the final chapter with Samson
???
Complete the final chapter with Eve
Complete the final chapter with Judas
Complete the final chapter with Cain
Complete the final chapter with ???
Complete the final chapter with Maggy
Complete Challenge 9
Complete Challenge 4
Complete Challenge 3
Complete Challenge 2
Complete Challenge 1
Complete Challenge 6
Complete the final chapter with Isaac
Complete Challenge 7
Kill mom but pass on 2 treasure room items
100% the game and hardmode (get all the achievements)
Beat Satan in Hardmode
Beat the game as Samson in Hardmode
Beat the game as all characters in Hardmode.
Beat the game as Eve in Hardmode
Beat the game as Judas in Hardmode
Beat the game as Cain in Hardmode
Beat the game as ??? in Hardmode, and good luck!
Beat the game as Magdalen in Hardmode
Beat Mom in Hardmode
Beat Moms Heart in Hardmode
Beat the boss in the Cathedral in Hardmode
Beat the Game in Hardmode!
Gain 7 Health upgrades from Eternal Hearts
Beat the game as Isaac in Hardmode