Full list of all 99 The Binding of Isaac achievements. It takes around 200 hours to unlock all of the achievements in the base game on Windows.
The base game contains 52 achievements, and there are 2 DLC packs containing 47 achievements.
Complete the depths without taking damage
Complete the caves without taking damage
Complete Sheol with Isaac
Complete Sheol with Eve
Complete Sheol with ???
Complete the full game with ???
Complete the womb without taking damage
100% the game
Complete Sheol with Judas
Complete Sheol with Maggy
Complete Sheol with Cain
Complete the full game 10 times
Complete the full game 9 times
You defeated Gish!
Complete the full game 8 times
Complete the full game 7 times
stay out of moms things!
ive lost my head one too many times...
Complete the full game 6 times
Find Krampus in Satans room for a gift!
Complete the full game 5 times
Dirty needles... eww
Call death upon all of them!
Complete the womb with Eve
Complete the full game 4 times
You defeated Steven!
Complete the full game 3 times
Complete the full game with Maggy
Give mom a taste of her own medicine!
Complete the full game 2 times
Complete the full game with Judas
You defeated C.H.A.D.!
Make a Super Meat Boy!
i lost mine in the arcade...
Complete the full game
Complete the full game with Cain
Defeat all bosses in the depths
kill mom...
Complete the basement without taking damage
Kids shouldnt play with matches...
Destroy the 7 Sins!
Collect 50+ pennies in one play through
Defeat all bosses in the caves
mom needs her pills! donate blood.
Complete the Caves
Collect 7+ container hearts in one play through
you dont wanna know where this bean has been...
Make 2 deals with the devil in one play through
Kids shouldnt play with dead things...
i like to break things...
Defeat all bosses in the basement
Complete the basement
???
Complete the final chapter with ???
Complete the final chapter with Eve
Complete the final chapter with Isaac
Complete the final chapter with Judas
Complete the final chapter with Maggy
Kill Satan with Samson
Complete the final chapter with Cain
Kill moms heart with Samson
Complete the final chapter with Samson
Kill mom but pass on 2 treasure room items
Complete Challenge 9
Complete Challenge 8
Complete Challenge 7
Complete Challenge 5
Complete Challenge 4
Complete Challenge 3
Complete Challenge 2
Complete Challenge 6
Complete Challenge 1
Beat the game as Cain in Hardmode
Beat the game as all characters in Hardmode.
100% the game and hardmode (get all the achievements)
Beat the game as Judas in Hardmode
Beat the game as ??? in Hardmode, and good luck!
Beat the game as Eve in Hardmode
Beat the game as Magdalen in Hardmode
Beat Satan in Hardmode
Beat the game as Samson in Hardmode
Beat the game as Isaac in Hardmode
Beat the Game in Hardmode!
Beat the boss in the Cathedral in Hardmode
Gain 7 Health upgrades from Eternal Hearts
Beat Moms Heart in Hardmode
Beat Mom in Hardmode