Full list of all 99 The Binding of Isaac achievements. It takes around 200 hours to unlock all of the achievements in the base game on Windows.
The base game contains 52 achievements, and there are 2 DLC packs containing 47 achievements.
100% the game
Complete Sheol with Eve
Complete Sheol with ???
Complete the depths without taking damage
Complete Sheol with Maggy
Complete the womb without taking damage
Complete Sheol with Judas
Complete Sheol with Cain
Give mom a taste of her own medicine!
Find Krampus in Satans room for a gift!
Complete the caves without taking damage
Complete Sheol with Isaac
Complete the full game with ???
Make a Super Meat Boy!
Complete the full game 10 times
Complete the full game 9 times
Complete the womb with Eve
Complete the full game 8 times
Complete the full game 7 times
Complete the full game 6 times
Complete the full game with Judas
You defeated Gish!
Complete the full game 5 times
Complete the full game 4 times
Complete the full game 3 times
Complete the full game 2 times
Complete the full game with Cain
You defeated C.H.A.D.!
i lost mine in the arcade...
ive lost my head one too many times...
Defeat all bosses in the depths
mom needs her pills! donate blood.
Complete the full game
Complete the full game with Maggy
You defeated Steven!
Dirty needles... eww
Kids shouldnt play with dead things...
Collect 50+ pennies in one play through
Call death upon all of them!
stay out of moms things!
kill mom...
Collect 7+ container hearts in one play through
Defeat all bosses in the caves
Destroy the 7 Sins!
Kids shouldnt play with matches...
Complete the Caves
Complete the basement without taking damage
you dont wanna know where this bean has been...
Make 2 deals with the devil in one play through
i like to break things...
Defeat all bosses in the basement
Complete the basement
Kill Satan with Samson
???
Complete Challenge 3
Complete the final chapter with ???
Complete Challenge 8
Complete Challenge 4
Complete the final chapter with Eve
Kill moms heart with Samson
Complete the final chapter with Samson
Complete the final chapter with Cain
Complete the final chapter with Isaac
Complete the final chapter with Maggy
Complete the final chapter with Judas
Kill mom but pass on 2 treasure room items
Complete Challenge 1
Complete Challenge 2
Complete Challenge 6
Complete Challenge 5
Complete Challenge 7
Complete Challenge 9
Beat Mom in Hardmode
Beat Moms Heart in Hardmode
Beat Satan in Hardmode
Beat the boss in the Cathedral in Hardmode
Beat the Game in Hardmode!
Gain 7 Health upgrades from Eternal Hearts
Beat the game as Isaac in Hardmode
Beat the game as Cain in Hardmode
Beat the game as Magdalen in Hardmode
Beat the game as Judas in Hardmode
Beat the game as Samson in Hardmode
Beat the game as Eve in Hardmode
Beat the game as ??? in Hardmode, and good luck!
Beat the game as all characters in Hardmode.
100% the game and hardmode (get all the achievements)