Full list of all 99 The Binding of Isaac achievements. It takes around 80-100 hours to unlock all of the achievements in the base game on Windows.
The base game contains 52 achievements, and there are 2 DLC packs containing 47 achievements.
100% the game
Complete Sheol with Eve
Complete Sheol with ???
Complete Sheol with Judas
You defeated Gish!
Complete Sheol with Cain
Complete Sheol with Maggy
Complete the full game with ???
Complete the womb with Eve
ive lost my head one too many times...
Give mom a taste of her own medicine!
Complete the full game 10 times
Complete the full game 8 times
Complete the full game 9 times
Complete the full game 7 times
Complete the full game 6 times
Complete Sheol with Isaac
Call death upon all of them!
Complete the full game 5 times
Complete the full game with Cain
Complete the caves without taking damage
Complete the depths without taking damage
Complete the womb without taking damage
Find Krampus in Satans room for a gift!
You defeated C.H.A.D.!
Complete the full game with Maggy
Complete the full game 4 times
Defeat all bosses in the depths
Kids shouldnt play with dead things...
Complete the full game 3 times
Complete the full game 2 times
Complete the full game with Judas
Complete the full game
Make a Super Meat Boy!
Dirty needles... eww
Complete the basement without taking damage
You defeated Steven!
i lost mine in the arcade...
kill mom...
Collect 50+ pennies in one play through
mom needs her pills! donate blood.
Make 2 deals with the devil in one play through
stay out of moms things!
Defeat all bosses in the caves
Kids shouldnt play with matches...
Destroy the 7 Sins!
Collect 7+ container hearts in one play through
Complete the Caves
Defeat all bosses in the basement
you dont wanna know where this bean has been...
i like to break things...
Complete the basement
Complete the final chapter with Samson
Complete the final chapter with Cain
Complete the final chapter with Maggy
Kill Satan with Samson
???
Complete the final chapter with Isaac
Complete the final chapter with Judas
Complete Challenge 3
Complete Challenge 1
Complete Challenge 4
Complete Challenge 6
Complete Challenge 5
Complete Challenge 8
Kill moms heart with Samson
Complete the final chapter with Eve
Complete the final chapter with ???
Complete Challenge 9
Complete Challenge 7
Complete Challenge 2
Kill mom but pass on 2 treasure room items
Beat Mom in Hardmode
Beat Moms Heart in Hardmode
Beat Satan in Hardmode
Beat the boss in the Cathedral in Hardmode
Beat the Game in Hardmode!
Gain 7 Health upgrades from Eternal Hearts
Beat the game as Isaac in Hardmode
Beat the game as Cain in Hardmode
Beat the game as Magdalen in Hardmode
Beat the game as Judas in Hardmode
Beat the game as Samson in Hardmode
Beat the game as Eve in Hardmode
Beat the game as ??? in Hardmode, and good luck!
Beat the game as all characters in Hardmode.
100% the game and hardmode (get all the achievements)