Full list of all 99 The Binding of Isaac achievements. It takes around 200 hours to unlock all of the achievements in the base game on Windows.
The base game contains 52 achievements, and there are 2 DLC packs containing 47 achievements.
Complete the womb without taking damage
100% the game
ive lost my head one too many times...
Make a Super Meat Boy!
Complete the depths without taking damage
Dirty needles... eww
Complete Sheol with ???
Complete Sheol with Eve
Call death upon all of them!
Complete Sheol with Isaac
Complete Sheol with Maggy
You defeated Steven!
Complete Sheol with Judas
Complete Sheol with Cain
Complete the full game with ???
You defeated Gish!
Complete the full game 10 times
Complete the caves without taking damage
Complete the full game 9 times
Complete the full game 8 times
Give mom a taste of her own medicine!
You defeated C.H.A.D.!
Complete the full game 7 times
Complete the full game 6 times
Complete the full game with Maggy
Complete the full game 5 times
mom needs her pills! donate blood.
Complete the full game 4 times
i lost mine in the arcade...
Complete the full game 3 times
Complete the full game with Cain
Complete the full game 2 times
Complete the full game with Judas
Complete the basement without taking damage
stay out of moms things!
Complete the womb with Eve
Complete the full game
Collect 50+ pennies in one play through
Kids shouldnt play with matches...
Kids shouldnt play with dead things...
kill mom...
Defeat all bosses in the depths
Destroy the 7 Sins!
Defeat all bosses in the caves
Find Krampus in Satans room for a gift!
Defeat all bosses in the basement
i like to break things...
Complete the Caves
Collect 7+ container hearts in one play through
Make 2 deals with the devil in one play through
you dont wanna know where this bean has been...
Complete the basement
???
Complete Challenge 9
Complete Challenge 8
Complete Challenge 7
Complete Challenge 6
Complete Challenge 5
Complete Challenge 4
Complete Challenge 3
Complete Challenge 2
Complete Challenge 1
Complete the final chapter with ???
Complete the final chapter with Eve
Complete the final chapter with Maggy
Complete the final chapter with Isaac
Complete the final chapter with Judas
Kill Satan with Samson
Complete the final chapter with Cain
Kill moms heart with Samson
Complete the final chapter with Samson
Kill mom but pass on 2 treasure room items
Beat the game as Magdalen in Hardmode
Beat the game as all characters in Hardmode.
100% the game and hardmode (get all the achievements)
Beat the game as Samson in Hardmode
Beat the game as Judas in Hardmode
Beat the game as Eve in Hardmode
Beat the game as Cain in Hardmode
Beat the game as ??? in Hardmode, and good luck!
Beat the Game in Hardmode!
Beat the game as Isaac in Hardmode
Beat Satan in Hardmode
Gain 7 Health upgrades from Eternal Hearts
Beat Mom in Hardmode
Beat Moms Heart in Hardmode
Beat the boss in the Cathedral in Hardmode