Full list of all 99 The Binding of Isaac achievements. It takes around 200 hours to unlock all of the achievements in the base game on Windows.
The base game contains 52 achievements, and there are 2 DLC packs containing 47 achievements.
Complete Sheol with ???
100% the game
Complete Sheol with Eve
Complete Sheol with Maggy
Complete the depths without taking damage
Complete the caves without taking damage
Complete Sheol with Cain
Complete Sheol with Isaac
Make a Super Meat Boy!
Complete Sheol with Judas
stay out of moms things!
Give mom a taste of her own medicine!
You defeated Gish!
Complete the full game with ???
ive lost my head one too many times...
Complete the full game 10 times
Complete the full game 9 times
Complete the womb without taking damage
Complete the full game 8 times
Complete the full game 7 times
Complete the full game 6 times
Complete the full game 5 times
Complete the full game 4 times
Complete the full game with Maggy
Complete the full game 3 times
Complete the full game with Judas
Complete the full game 2 times
Complete the womb with Eve
i lost mine in the arcade...
Kids shouldnt play with dead things...
Dirty needles... eww
You defeated Steven!
Defeat all bosses in the depths
You defeated C.H.A.D.!
mom needs her pills! donate blood.
Complete the full game
Complete the full game with Cain
Make 2 deals with the devil in one play through
Complete the basement without taking damage
Call death upon all of them!
Destroy the 7 Sins!
kill mom...
Find Krampus in Satans room for a gift!
Kids shouldnt play with matches...
you dont wanna know where this bean has been...
Defeat all bosses in the caves
Collect 50+ pennies in one play through
Defeat all bosses in the basement
i like to break things...
Complete the Caves
Collect 7+ container hearts in one play through
Complete the basement
???
Complete the final chapter with ???
Complete the final chapter with Maggy
Complete the final chapter with Eve
Complete the final chapter with Samson
Complete the final chapter with Cain
Kill Satan with Samson
Kill moms heart with Samson
Complete the final chapter with Isaac
Complete the final chapter with Judas
Complete Challenge 9
Complete Challenge 6
Complete Challenge 7
Complete Challenge 8
Kill mom but pass on 2 treasure room items
Complete Challenge 3
Complete Challenge 1
Complete Challenge 2
Complete Challenge 4
Complete Challenge 5
100% the game and hardmode (get all the achievements)
Beat the game as ??? in Hardmode, and good luck!
Beat the game as all characters in Hardmode.
Beat the game as Magdalen in Hardmode
Beat the game as Eve in Hardmode
Beat the game as Samson in Hardmode
Beat the game as Cain in Hardmode
Beat the game as Judas in Hardmode
Beat the Game in Hardmode!
Beat the game as Isaac in Hardmode
Beat Satan in Hardmode
Gain 7 Health upgrades from Eternal Hearts
Beat Mom in Hardmode
Beat Moms Heart in Hardmode
Beat the boss in the Cathedral in Hardmode