Here is the full list of all 48 Subterrain achievements.
Complete the tutorial section of the game at MPO Prison.
Beat the game using the "Easy Mode" or higher difficulty setting.
Beat the game using the "Normal Mode" or higher difficulty setting.
Explore every floor and every district of MPO.
Discover the space port for MPO: the Murray Space Center.
Use toilets 30 times in one game.
Discover the Leo residential district.
Discover the Aries residential district.
Discover the Gemini residential district.
Collect ore 100 times using the extractor at MPO's mine.
Kill 30 Big Fat enemies.
Complete 50 research projects at Herbert Research.
Produce fruits or veggies 100 times at MPO's biosphere.
Destroy 50 cocoons before enemies pop out of them.
Discover the Pisces residential district.
Kill 40 Spitter enemies.
Kill 80 Brain Bug enemies.
Discover the shopping district of MPO: Spirit Plaza.
Produce 80 items using 3D printer or bio combiner in Nilson Engineering.
Discover the sprawling business of Mr. Bigelow: the Solar Casino.
Survive for more than 120 hours in a single game.
Discover the business of the Burlington family: the Carson Hotel.
Produce 30 items using the 3D printer or bio combiner at Nilson Engineering.
Kill 100 enemies of any type.
Discover a residential district of MPO: Viking Square.
Survive for more than 72 hours in a single game.
Produce fruits or veggies 50 times at MPO's biosphere.
Collect ore 50 times using the extractor at MPO's mine.
Kill 50 enemies of any type.
Discover the ore extraction facilities of MPO's mine.
Discover the agricultural facilities of MPO's biosphere.
Produce 10 items using 3D printer or bio combiner in Nilson Engineering.
Kill 10 enemies of any type.
Complete 20 research projects at Herbert Research.
Discover the 3D printing facilities of Nilson Engineering.
Produce fruits or veggies 10 times at MPO's biosphere.
Discover Dr. West's old workplace: the Herbert Research Center.
Survive for 24 hours in a single game.
Collect ore 10 times using the extractor at MPO's mine.
Complete 10 research projects at Herbert Research.
Beat the game using the "Hardcore Mode" or higher difficulty setting.
Beat the game using the "Nightmare Mode" difficulty setting.
Beat the game with the "Permanent Death" option enabled.