Here is the full list of all 48 Subterrain achievements.
Beat the game using the "Easy Mode" or higher difficulty setting.
Beat the game using the "Normal Mode" or higher difficulty setting.
Collect ore 100 times using the extractor at MPO's mine.
Produce fruits or veggies 100 times at MPO's biosphere.
Explore every floor and every district of MPO.
Discover the space port for MPO: the Murray Space Center.
Discover the Pisces residential district.
Collect ore 50 times using the extractor at MPO's mine.
Produce fruits or veggies 50 times at MPO's biosphere.
Discover the Leo residential district.
Use toilets 30 times in one game.
Destroy 50 cocoons before enemies pop out of them.
Discover the Aries residential district.
Discover the Gemini residential district.
Discover the sprawling business of Mr. Bigelow: the Solar Casino.
Complete 50 research projects at Herbert Research.
Kill 80 Brain Bug enemies.
Produce 80 items using 3D printer or bio combiner in Nilson Engineering.
Kill 30 Big Fat enemies.
Discover the shopping district of MPO: Spirit Plaza.
Kill 40 Spitter enemies.
Collect ore 10 times using the extractor at MPO's mine.
Discover a residential district of MPO: Viking Square.
Produce 30 items using the 3D printer or bio combiner at Nilson Engineering.
Survive for more than 120 hours in a single game.
Complete 20 research projects at Herbert Research.
Produce fruits or veggies 10 times at MPO's biosphere.
Produce 10 items using 3D printer or bio combiner in Nilson Engineering.
Kill 100 enemies of any type.
Discover the business of the Burlington family: the Carson Hotel.
Survive for more than 72 hours in a single game.
Discover the ore extraction facilities of MPO's mine.
Kill 50 enemies of any type.
Discover the agricultural facilities of MPO's biosphere.
Complete 10 research projects at Herbert Research.
Discover Dr. West's old workplace: the Herbert Research Center.
Kill 10 enemies of any type.
Survive for 24 hours in a single game.
Discover the 3D printing facilities of Nilson Engineering.
Complete the tutorial section of the game at MPO Prison.
Beat the game using the "Hardcore Mode" or higher difficulty setting.
Beat the game using the "Nightmare Mode" difficulty setting.
Beat the game with the "Permanent Death" option enabled.