Here is the full list of all 48 Subterrain achievements.
Beat the game using the "Easy Mode" or higher difficulty setting.
Collect ore 100 times using the extractor at MPO's mine.
Produce fruits or veggies 100 times at MPO's biosphere.
Explore every floor and every district of MPO.
Discover the space port for MPO: the Murray Space Center.
Collect ore 50 times using the extractor at MPO's mine.
Kill 30 Big Fat enemies.
Produce fruits or veggies 50 times at MPO's biosphere.
Destroy 50 cocoons before enemies pop out of them.
Collect ore 10 times using the extractor at MPO's mine.
Discover the Gemini residential district.
Produce fruits or veggies 10 times at MPO's biosphere.
Use toilets 30 times in one game.
Discover the Leo residential district.
Kill 80 Brain Bug enemies.
Discover the Pisces residential district.
Kill 40 Spitter enemies.
Discover the shopping district of MPO: Spirit Plaza.
Discover the Aries residential district.
Complete 50 research projects at Herbert Research.
Discover the sprawling business of Mr. Bigelow: the Solar Casino.
Produce 80 items using 3D printer or bio combiner in Nilson Engineering.
Produce 30 items using the 3D printer or bio combiner at Nilson Engineering.
Survive for more than 120 hours in a single game.
Kill 100 enemies of any type.
Discover a residential district of MPO: Viking Square.
Complete 20 research projects at Herbert Research.
Discover the agricultural facilities of MPO's biosphere.
Discover the ore extraction facilities of MPO's mine.
Survive for more than 72 hours in a single game.
Kill 50 enemies of any type.
Discover the business of the Burlington family: the Carson Hotel.
Produce 10 items using 3D printer or bio combiner in Nilson Engineering.
Complete 10 research projects at Herbert Research.
Discover the 3D printing facilities of Nilson Engineering.
Kill 10 enemies of any type.
Discover Dr. West's old workplace: the Herbert Research Center.
Survive for 24 hours in a single game.
Complete the tutorial section of the game at MPO Prison.
Beat the game using the "Normal Mode" or higher difficulty setting.
Beat the game using the "Hardcore Mode" or higher difficulty setting.
Beat the game using the "Nightmare Mode" difficulty setting.
Beat the game with the "Permanent Death" option enabled.