All achievements can be done in one playthrough sans challenges. Again, play on cadet difficulty and remain undetected.
You'll encounter an officer preparing to burn books (location in video below). Give him an eye shot to unlock:
Read This!Infiltration - Eye shot the book burning Officer

An island sits off in the distance with a number of explosive barrels. Light them up to unlock:
You'll need to perform a multi-kill in the auditorium. Do this to unlock:
DebriefedInfiltration - Multi-Kill the Officers during the tactical briefing in the auditorium

https://www.youtube.com/watch?time_continue=204&v=Bh...
You'll need to call and eliminate the Valkyrie Squad with the Neunfaust. Wait for the reinforcements to arrive and then kill them all. Please note that a few stragglers follow behind the vehicles. Pick them off without exiting through the gate. This will unlock:
Faust of FuryInfiltration - Kill the Valkyrie Squad reinforcements using only the Neunfaust

Completing the mission undetected will net you:
UntouchableInfiltration - Complete the Mission without being shot by a Sniper

The challenges for this mission include:
- Man in the High Tower: Kill 20 enemies from towers with flags
- A Touch of Glass: Kill 3 enemies with dropped chandeliers (Can be combined with Shhh!)
- Shhh!: Ghost-kill 5 enemies in the library (Can be combined with A Touch of Glass)
- Don't Stop Breathing: Complete the mission without using Empty Lung
- Boom! Headshot!: Kill all Valkyrie Squad members with a headshot in under 12 minutes
The last one is tricky, but follow the below video to get it done.
Doing so will unlock:
Full MarksInfiltration - Complete all the Challenges

https://www.youtube.com/watch?time_continue=250&v=l1...
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