Here is the full list of all 12 Resident Evil 4 achievements. It takes around 20-25 hours to unlock all of the achievements on Windows.
Clear the game on the highest difficulty.
Acquire all of the bottle caps in the game.
Turn the tables on Verdugo, the right hand of Salazar.
Ring the mysterious bell. What happens after that, is up to you.
Summon the master of the lake. Don't rock the boat.
Outmaneuver the rampaging beast, El Gigante.
Rescue the president's daughter, Ashley. Afterwards, the real fun begins.
Defeat the village chief in battle.
Defeat Salazar, and make your escape from the castle.
Defeat Krauser, your former partner, in battle.
Defeat Saddler in battle, and escape from the nightmare.
Acquire all of the costumes in the game.