Here is the full list of all 22 Profane achievements.
Complete the tutorial
Beat Tutoriaal
Beat Khalepo
Beat Mobus
Beat Drakhul
Beat Duhm
Beat Ylaudit
Beat Nuraanag
Beat Sentiel
Beat Cindael
Beat Garodal
Unlock the 'Doom' ending
Unlock the 'Freedom' ending
Win a game in Challenge Mode
Use every ability
Beat a Boss with no remaining time
Beat a Boss without taking damage
Have a 5 Daily win streak
Die 10 times
Pick 50 souls
Beat a boss without actives and passives
Complete all achievements