Here is the full list of all 22 Profane achievements.
Beat Garodal
Unlock the 'Freedom' ending
Beat Cindael
Beat Sentiel
Beat Nuraanag
Beat Ylaudit
Beat Duhm
Beat Mobus
Beat Drakhul
Die 10 times
Beat Khalepo
Pick 50 souls
Beat Tutoriaal
Beat a Boss with no remaining time
Complete the tutorial
Unlock the 'Doom' ending
Win a game in Challenge Mode
Use every ability
Beat a Boss without taking damage
Have a 5 Daily win streak
Beat a boss without actives and passives
Complete all achievements